Definitely!
In fact, for loads of really important elements (and particular isotopes of elements) used for medicine, the only way we have of making them is to manufacture them in nuclear reactors and particle accelerators. All the natural resources of these materials would have radioactively decayed away long long ago.
Things we manufacture tend to be fairly radioactive though, and it takes a lot of effort (and expense!) to make a very small amount, so it’s no use for turning Lead into Gold to make money!
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